› 4l1p

X-ray diffraction
2.12Å resolution

Crystal Structure of Human Rtf1 Plus3 domain

Released:
DOI: 10.2210/pdb4l1p/pdb
PDB entry 4l1p coloured by chain, front view.
PDB entry 4l1p coloured by chain, side view.
PDB entry 4l1p coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural basis for Spt5-mediated recruitment of the Paf1 complex to chromatin.
Wier AD, Mayekar MK, Héroux A, Arndt KM, VanDemark AP
Proc Natl Acad Sci U S A 110 17290-5 (2013)
PMID: 24101474

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-187679 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
RNA polymerase-associated protein RTF1 homolog Chains: A, B
Molecule details ›
Chains: A, B
Length: 138 amino acids
Theoretical weight: 15.92 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q92541 (Residues: 353-484; Coverage: 19%)
Gene names: KIAA0252, RTF1
Sequence domains: Plus-3 domain
Structure domains: Plus-3 domain

Ligands and Environments

1 bound ligand:
Ligand GOL 5 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E DW
Spacegroup: P212121
Unit cell:
a: 33.636Å b: 68.025Å c: 116.972Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.208 0.206 0.24
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

12 review citations

Getting up to speed with transcription elongation by RNA polymerase II.
Jonkers et al. (2015)
11 more

2 mentions without citation

Structural basis for Spt5-mediated recruitment of the Paf1 complex to chromatin.
Wier et al. (2013)
1 more