X-ray diffraction
2Å resolution

BRDT in complex with Dinaciclib


Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Bromodomain testis-specific protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 117 amino acids
Theoretical weight: 13.95 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q58F21 (Residues: 21-137; Coverage: 12%)
Gene name: BRDT
Sequence domains: Bromodomain
Structure domains: Bromodomain-like

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P21
Unit cell:
a: 64.72Å b: 29.95Å c: 71.38Å
α: 90° β: 94.12° γ: 90°
R R work R free
0.211 0.209 0.253
Expression system: Escherichia coli