PDBe 4jjh

X-ray diffraction
2.25Å resolution

Crystal structure of the D1 domain from human Nectin-4 extracellular fragment [PSI-NYSGRC-005624]

Source organism: Homo sapiens
Entry authors: Kumar PR, Bonanno J, Ahmed M, Banu R, Bhosle R, Calarese D, Celikigil A, Chamala S, Chan MK, Chowdhury S, Fiser A, Garforth S, Glenn AS, Hillerich B, Khafizov K, Love J, Patel H, Seidel R, Stead M, Toro R, Nathenson SG, Almo SC, New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Processed poliovirus receptor-related protein 4 Chains: A, B
Molecule details ›
Chains: A, B
Length: 133 amino acids
Theoretical weight: 14.44 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
  • Canonical: Q96NY8 (Residues: 32-153; Coverage: 26%)
Gene names: LNIR, NECTIN4, PRR4, PVRL4
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P41
Unit cell:
a: 35.193Å b: 35.193Å c: 205.331Å
α: 90° β: 90° γ: 90°
R R work R free
0.226 0.222 0.292
Expression system: Trichoplusia ni