4jif

X-ray diffraction
1.7Å resolution

Co-crystal structure of ICAP1 PTB domain in complex with a KRIT1 peptide

Released:
Source organism: Homo sapiens
Primary publication:
Cocrystal structure of the ICAP1 PTB domain in complex with a KRIT1 peptide.
Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 69 494-8 (2013)
PMID: 23695561

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
Non-polymer only dimer (preferred)
Non-polymer only tetramer
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Integrin beta-1-binding protein 1 Chain: A
Molecule details ›
Chain: A
Length: 154 amino acids
Theoretical weight: 16.91 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O14713 (Residues: 49-200; Coverage: 76%)
Gene names: ICAP1, ITGB1BP1
Krev interaction trapped protein 1 Chain: B
Molecule details ›
Chain: B
Length: 34 amino acids
Theoretical weight: 3.73 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O00522 (Residues: 170-198; Coverage: 4%)
Gene names: CCM1, KRIT1

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P6522
Unit cell:
a: 81.017Å b: 81.017Å c: 89.583Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.197 0.196 0.226
Expression system: Escherichia coli