4j9z

X-ray diffraction
1.66Å resolution

Calcium-calmodulin complexed with the calmodulin binding domain from a small conductance potassium channel splice variant and NS309

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Small conductance calcium-activated potassium channel protein 2 Chain: B
Molecule details ›
Chain: B
Length: 102 amino acids
Theoretical weight: 12.24 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: P70604 (Residues: 396-487; Coverage: 16%)
Gene name: Kcnn2
Sequence domains: Calmodulin binding domain
Structure domains: Helix Hairpins
Calmodulin-1 Chain: R
Molecule details ›
Chain: R
Length: 149 amino acids
Theoretical weight: 16.85 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: P0DP29 (Residues: 1-149; Coverage: 100%)
Gene names: CaMI, Calm, Calm1, Cam, Cam1
Sequence domains: EF-hand domain pair

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X6A
Spacegroup: C2
Unit cell:
a: 77.2Å b: 66.85Å c: 64.83Å
α: 90° β: 93.81° γ: 90°
R-values:
R R work R free
0.192 0.191 0.221
Expression system: Escherichia coli