X-ray diffraction
2.7Å resolution

Crystal structure of a fusion protein containing the NBD of Hsp70 and the middle domain of Hip

Source organisms:
Primary publication:
Structure and function of Hip, an attenuator of the Hsp70 chaperone cycle.
Nat. Struct. Mol. Biol. 20 929-35 (2013)
PMID: 23812373

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
homo dimer
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Heat shock 70 kDa protein 1A; Hsc70-interacting protein Chain: A
Molecule details ›
Chain: A
Length: 561 amino acids
Theoretical weight: 62.42 KDa
Source organisms: Expression system: Escherichia coli BL21(DE3)
  • Canonical: P0DMV8 (Residues: 1-382; Coverage: 60%)
  • Canonical: P50503 (Residues: 77-247; Coverage: 47%)
Gene names: Fam10a1, HSP72, HSPA1, HSPA1A, HSX70, Hip, St13
Structure domains:

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-2
Spacegroup: P41
Unit cell:
a: 65.596Å b: 65.596Å c: 141.47Å
α: 90° β: 90° γ: 90°
R R work R free
0.197 0.194 0.261
Expression system: Escherichia coli BL21(DE3)