PDBe 4j4q

X-ray diffraction
2.65Å resolution

Crystal structure of active conformation of GPCR opsin stabilized by octylglucoside

Released:
Source organism: Bos taurus
Primary publication:
Opsin, a structural model for olfactory receptors?
Angew. Chem. Int. Ed. Engl. 52 11021-4 (2013)
PMID: 24038729

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Rhodopsin Chain: A
Molecule details ›
Chain: A
Length: 348 amino acids
Theoretical weight: 39.03 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P02699 (Residues: 1-348; Coverage: 100%)
Gene name: RHO
Sequence domains:
Structure domains: Rhopdopsin 7-helix transmembrane proteins
Guanine nucleotide-binding protein G(t) subunit alpha-1 Chain: B
Molecule details ›
Chain: B
Length: 11 amino acids
Theoretical weight: 1.26 KDa
Source organism: Bos taurus
Expression system: Not provided
UniProt:
  • Canonical: P04695 (Residues: 340-350; Coverage: 3%)
Gene name: GNAT1

Ligands and Environments

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.2
Spacegroup: R32
Unit cell:
a: 241.265Å b: 241.265Å c: 109.561Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.218 0.217 0.23
Expression system: Not provided