› 4iyf

X-ray diffraction
1.8Å resolution

Insulin glargine crystal structure 2

Released:
DOI: 10.2210/pdb4iyf/pdb
PDB entry 4iyf coloured by chain, front view.
PDB entry 4iyf coloured by chain, side view.
PDB entry 4iyf coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Barba de la Rosa AP, Lara-Gonzalez S, Montero-Moran GM, Escobedo-Moratilla A

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134182 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Insulin A chain Chain: A
Molecule details ›
Chain: A
Length: 21 amino acids
Theoretical weight: 2.33 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P01308 (Residues: 90-109; Coverage: 23%)
Gene name: INS
Insulin B chain Chain: B
Molecule details ›
Chain: B
Length: 29 amino acids
Theoretical weight: 3.33 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P01308 (Residues: 25-53; Coverage: 34%)
Gene name: INS
Sequence domains: Insulin/IGF/Relaxin family

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007 HF
Spacegroup: I213
Unit cell:
a: 77.3Å b: 77.3Å c: 77.3Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.216 0.213 0.242
Expression system: Escherichia coli

Quick links