4hpm

X-ray diffraction
1.85Å resolution

PCGF1 Ub fold (RAWUL)/BCORL1 PUFD Complex

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
BCL-6 corepressor-like protein 1 Chains: A, C
Molecule details ›
Chains: A, C
Length: 122 amino acids
Theoretical weight: 14.02 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q5H9F3 (Residues: 1594-1711; Coverage: 7%)
Gene name: BCORL1
Structure domains: BCL-6 corepressor, PCGF1 binding domain
Polycomb group RING finger protein 1 Chains: B, D
Molecule details ›
Chains: B, D
Length: 93 amino acids
Theoretical weight: 11.07 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9BSM1 (Residues: 167-255; Coverage: 34%)
Gene names: NSPC1, PCGF1, RNF68
Sequence domains: RAWUL domain RING finger- and WD40-associated ubiquitin-like
Structure domains: Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-F
Spacegroup: P21
Unit cell:
a: 52.784Å b: 65.794Å c: 56.517Å
α: 90° β: 94.73° γ: 90°
R-values:
R R work R free
0.202 0.199 0.247
Expression system: Escherichia coli BL21(DE3)