4hpl

X-ray diffraction
2Å resolution

PCGF1 Ub fold (RAWUL)/BCOR PUFD Complex

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
BCL-6 corepressor Chain: A
Molecule details ›
Chain: A
Length: 119 amino acids
Theoretical weight: 13.68 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q6W2J9 (Residues: 1634-1748; Coverage: 7%)
Gene names: BCOR, KIAA1575
Sequence domains: BCORL-PCGF1-binding domain
Structure domains: BCL-6 corepressor, PCGF1 binding domain
Polycomb group RING finger protein 1 Chain: B
Molecule details ›
Chain: B
Length: 93 amino acids
Theoretical weight: 11.07 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9BSM1 (Residues: 167-255; Coverage: 34%)
Gene names: NSPC1, PCGF1, RNF68
Sequence domains: RAWUL domain RING finger- and WD40-associated ubiquitin-like
Structure domains: Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 4.2.2
Spacegroup: P62
Unit cell:
a: 67.681Å b: 67.681Å c: 75.742Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.217 0.212 0.261
Expression system: Escherichia coli BL21(DE3)