PDBe 4hoo

X-ray diffraction
2.5Å resolution

Crystal structure of human JMJD2D/KDM4D apoenzyme

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lysine-specific demethylase 4D Chains: A, B
Molecule details ›
Chains: A, B
Length: 330 amino acids
Theoretical weight: 38.02 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q6B0I6 (Residues: 12-341; Coverage: 63%)
Gene names: JHDM3D, JMJD2D, KDM4D
Sequence domains:
Structure domains: Cupin

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-G
Spacegroup: P32
Unit cell:
a: 73.119Å b: 73.119Å c: 136.028Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.209 0.207 0.246
Expression system: Escherichia coli BL21(DE3)