PDBe 4hgc

X-ray diffraction
1.29Å resolution

Crystal structure of bovine trypsin complexed with sfti-1 analog containing a peptoid residue at position p1

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Cationic trypsin Chain: A
Molecule details ›
Chain: A
Length: 223 amino acids
Theoretical weight: 23.32 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P00760 (Residues: 24-246; Coverage: 97%)
Sequence domains: Trypsin
Structure domains: Trypsin-like serine proteases
Trypsin inhibitor 1 Chain: I
Molecule details ›
Chain: I
Length: 14 amino acids
Theoretical weight: 1.53 KDa
Source organism: Helianthus annuus
Expression system: Not provided
UniProt:
  • Canonical: Q4GWU5 (Residues: 40-53; Coverage: 45%)
Gene name: sfti1

Ligands and Environments

3 bound ligands:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X11
Spacegroup: P212121
Unit cell:
a: 60.12Å b: 64.14Å c: 70.04Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.127 0.126 0.157
Expression system: Not provided