PDBe 4h88

X-ray diffraction
1.9Å resolution

Structure of POM1 FAB fragment complexed with mouse PrPc Fragment 120-230

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Major prion protein Chain: A
Molecule details ›
Chain: A
Length: 111 amino acids
Theoretical weight: 13.18 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P04925 (Residues: 120-230; Coverage: 48%)
Gene names: Prn-p, Prnp, Prp
POM1 FAB CHAIN H Chain: H
Molecule details ›
Chain: H
Length: 218 amino acids
Theoretical weight: 23.4 KDa
Source organism: Mus musculus
Structure domains: Immunoglobulins
POM1 FAB CHAIN L Chain: L
Molecule details ›
Chain: L
Length: 213 amino acids
Theoretical weight: 23.51 KDa
Source organism: Mus musculus
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-2
Spacegroup: C2
Unit cell:
a: 83.406Å b: 107.331Å c: 75.443Å
α: 90° β: 95.27° γ: 90°
R-values:
R R work R free
0.201 0.199 0.234
Expression system: Escherichia coli