› 4grk

X-ray diffraction
1.68Å resolution

Crystal Structure of C-lobe of Bovine lactoferrin Complexed with ketorolac at 1.68 A Resolution

Released:
DOI: 10.2210/pdb4grk/pdb
PDB 4grk coloured by chain and viewed from the front.
PDB 4grk coloured by chain and viewed from the side.
PDB 4grk coloured by chain and viewed from the top.
Source organism: Bos taurus
Entry authors: Gautam L, Shukla PK, Sinha M, Kaur P, Sharma S, Singh TP

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (4 distinct):
Lactotransferrin Chain: A
Molecule details ›
Chain: A
Length: 335 amino acids
Theoretical weight: 36.62 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P24627 (Residues: 361-695; Coverage: 49%)
Gene name: LTF
Sequence domains: Transferrin
Structure domains: Periplasmic binding protein-like II
Lactotransferrin Chain: B
Molecule details ›
Chain: B
Length: 6 amino acids
Theoretical weight: 653 Da
Source organism: Bos taurus
UniProt:
  • Canonical: P24627 (Residues: 700-705; Coverage: 1%)
Gene name: LTF

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
7 bound ligands:
Ligand NAG 1 x NAG
Ligand ZN 2 x ZN
Ligand FE 1 x FE
Ligand CO3 1 x CO3
Ligand SO4 1 x SO4
Ligand GOL 2 x GOL
Ligand KTR 1 x KTR
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: P21
Unit cell:
a: 62.615Å b: 49.953Å c: 65.504Å
α: 90° β: 107.22° γ: 90°
R-values:
R R work R free
0.157 0.155 0.205

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