4g0h

X-ray diffraction
3.6Å resolution

Crystal structure of the N-terminal domain of Helicobacter pylori CagA protein

Released:

Function and Biology Details

Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cytotoxicity-associated immunodominant antigen Chain: A
Molecule details ›
Chain: A
Length: 916 amino acids
Theoretical weight: 103.01 KDa
Source organism: Helicobacter pylori 26695
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P55980 (Residues: 1-884; Coverage: 75%)
Gene names: HP_0547, cag26, cagA, cai
Structure domains: Four Helix Bundle (Hemerythrin (Met), subunit A)

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P41212
Unit cell:
a: 97.83Å b: 97.83Å c: 245.39Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.329 0.329 0.341
Expression system: Escherichia coli BL21