PDBe 4fii

X-ray diffraction
2Å resolution

Catalytic domain of human PAK4 with RPKPLVDP peptide

Released:

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Serine/threonine-protein kinase PAK 4 Chain: A
Molecule details ›
Chain: A
Length: 346 amino acids
Theoretical weight: 39.12 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O96013 (Residues: 286-591; Coverage: 52%)
  • Best match: O96013-2 (Residues: 109-426)
Gene names: KIAA1142, PAK4
Sequence domains: Protein kinase domain
Structure domains:
Serine/threonine-protein kinase PAK 4 Chain: B
Molecule details ›
Chain: B
Length: 8 amino acids
Theoretical weight: 923 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: O96013 (Residues: 49-56; Coverage: 1%)
Gene names: KIAA1142, PAK4

Ligands and Environments

No bound ligands

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X6A
Spacegroup: P41212
Unit cell:
a: 61.557Å b: 61.557Å c: 181.771Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.203 0.201 0.24
Expression systems:
  • Escherichia coli
  • Not provided