4fif

X-ray diffraction
2.6Å resolution

Catalytic domain of human PAK4 with RPKPLVDP peptide

Released:

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
Non-polymer only dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Serine/threonine-protein kinase PAK 4 Chains: A, B
Molecule details ›
Chains: A, B
Length: 346 amino acids
Theoretical weight: 39.12 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O96013 (Residues: 286-591; Coverage: 52%)
  • Best match: O96013-2 (Residues: 109-426)
Gene names: KIAA1142, PAK4
Sequence domains: Protein kinase domain
Structure domains:
Serine/threonine-protein kinase PAK 4 Chains: C, D
Molecule details ›
Chains: C, D
Length: 8 amino acids
Theoretical weight: 923 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: O96013 (Residues: 49-56; Coverage: 1%)
Gene names: KIAA1142, PAK4

Ligands and Environments

1 bound ligand:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P3
Unit cell:
a: 141.411Å b: 141.411Å c: 61.624Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.207 0.206 0.227
Expression systems:
  • Escherichia coli
  • Not provided