PDBe 4f1i

X-ray diffraction
2.5Å resolution

Crystal structure of SeMet TDP2 from Caenorhabditis elegans

Released:
Source organism: Caenorhabditis elegans
Primary publication:
Structural basis for recognition of 5'-phosphotyrosine adducts by Tdp2.
OpenAccess logo Nat. Struct. Mol. Biol. 19 1372-7 (2012)
PMID: 23104058

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
5'-tyrosyl-DNA phosphodiesterase Chain: A
Molecule details ›
Chain: A
Length: 362 amino acids
Theoretical weight: 41.51 KDa
Source organism: Caenorhabditis elegans
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9XWG3 (Residues: 21-362; Coverage: 95%)
Gene name: Y63D3A.4
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 4.2.2
Spacegroup: P41212
Unit cell:
a: 100.685Å b: 100.685Å c: 121.375Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.184 0.182 0.229
Expression system: Escherichia coli