PDBe 4dbp

X-ray diffraction
2.2Å resolution

Myosin VI nucleotide-free (MDINSERT2) D179Y crystal structure

Released:
Entry authors: Pylypenko O, Sweeney HL, Houdusse A

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Unconventional myosin-VI Chain: A
Molecule details ›
Chain: A
Length: 814 amino acids
Theoretical weight: 93.08 KDa
Source organism: Sus scrofa
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q29122 (Residues: 2-816; Coverage: 65%)
Gene name: MYO6
Calmodulin Chain: C
Molecule details ›
Chain: C
Length: 149 amino acids
Theoretical weight: 16.83 KDa
Source organism: Drosophila melanogaster
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P62152 (Residues: 1-149; Coverage: 100%)
Gene names: CG8472, Cam
Sequence domains: EF-hand domain pair

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P21
Unit cell:
a: 68.6Å b: 104.39Å c: 90.02Å
α: 90° β: 91.15° γ: 90°
R-values:
R R work R free
0.165 0.163 0.218
Expression system: Spodoptera frugiperda