PDBe 4cdo

X-ray diffraction
2.5Å resolution

Crystal structure of PQBP1 bound to spliceosomal U5-15kD


Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Polyglutamine-binding protein 1; Thioredoxin-like protein 4A Chains: A, C
Molecule details ›
Chains: A, C
Length: 185 amino acids
Theoretical weight: 21.33 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P83876 (Residues: 4-138; Coverage: 95%)
  • Canonical: O60828 (Residues: 224-265; Coverage: 16%)
  • nullnull
Gene names: DIM1, JM26, NPW38, PQBP1, TXNL4, TXNL4A
Sequence domains: Mitosis protein DIM1
Structure domains: Glutaredoxin

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL41XU
Spacegroup: P21
Unit cell:
a: 59.36Å b: 53.7Å c: 66.19Å
α: 90° β: 89.95° γ: 90°
R R work R free
0.19 0.187 0.238
Expression system: Escherichia coli BL21(DE3)