4cc0

X-ray diffraction
2.32Å resolution

Notch ligand, Jagged-1, contains an N-terminal C2 domain

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein jagged-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 312 amino acids
Theoretical weight: 34.81 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P78504 (Residues: 32-335; Coverage: 26%)
Gene names: JAG1, JAGL1
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P1
Unit cell:
a: 55.98Å b: 60.25Å c: 62.65Å
α: 92.59° β: 104.44° γ: 106.67°
R-values:
R R work R free
0.219 0.218 0.246
Expression system: Homo sapiens