PDBe 4bwq

X-ray diffraction
2.1Å resolution

Crystal structure of U5-15kD in a complex with PQBP1

Released:

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Thioredoxin-like protein 4A Chains: A, C, E, G
Molecule details ›
Chains: A, C, E, G
Length: 142 amino acids
Theoretical weight: 16.74 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P83876 (Residues: 4-137; Coverage: 94%)
Gene names: DIM1, TXNL4, TXNL4A
Sequence domains: Mitosis protein DIM1
Structure domains: Glutaredoxin
Polyglutamine-binding protein 1 Chains: B, D, F, H
Molecule details ›
Chains: B, D, F, H
Length: 43 amino acids
Theoretical weight: 4.61 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O60828 (Residues: 223-265; Coverage: 16%)
Gene names: JM26, NPW38, PQBP1

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL41XU
Spacegroup: P2
Unit cell:
a: 77.22Å b: 40.04Å c: 118.77Å
α: 90° β: 93.45° γ: 90°
R-values:
R R work R free
0.189 0.186 0.252
Expression system: Escherichia coli BL21(DE3)