PDBe 4bsn

X-ray diffraction
4.1Å resolution

Crystal structure of the Nuclear Export Receptor CRM1 (exportin-1) lacking the C-terminal helical extension at 4.1A

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Exportin-1 Chain: A
Molecule details ›
Chain: A
Length: 1032 amino acids
Theoretical weight: 118.86 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O14980 (Residues: 1-1032; Coverage: 96%)
Gene names: CRM1, XPO1
Sequence domains:

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-2
Spacegroup: C2221
Unit cell:
a: 146.96Å b: 246.75Å c: 106.34Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.276 0.275 0.298
Expression system: Escherichia coli