X-ray diffraction
2.1Å resolution

Crystal structure of ID2 HLH homodimer at 2.1A resolution


Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
DNA-binding protein inhibitor ID-2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 97 amino acids
Theoretical weight: 10.84 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
  • Canonical: Q02363 (Residues: 1-82; Coverage: 61%)
Gene names: BHLHB26, ID2
Sequence domains: Helix-loop-helix DNA-binding domain
Structure domains: Helix-loop-helix DNA-binding domain

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P3221
Unit cell:
a: 51.622Å b: 51.622Å c: 111.474Å
α: 90° β: 90° γ: 120°
R R work R free
0.227 0.225 0.25
Expression system: Escherichia coli BL21(DE3)