X-ray diffraction
2.28Å resolution

The crystal structure of the ING4 dimerization domain reveals the functional organization of the ING family of chromatin binding proteins.


Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Inhibitor of growth protein 4 Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 104 amino acids
Theoretical weight: 12.4 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
  • Canonical: Q9UNL4 (Residues: 2-105; Coverage: 42%)
Gene names: ING4, My036
Structure domains: Helix Hairpins

Ligands and Environments

No bound ligands
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: C222
Unit cell:
a: 128.45Å b: 186.6Å c: 62.22Å
α: 90° β: 90° γ: 90°
R R work R free
0.207 0.205 0.256
Expression system: Escherichia coli BL21(DE3)