4afl

X-ray diffraction
2.28Å resolution

The crystal structure of the ING4 dimerization domain reveals the functional organization of the ING family of chromatin binding proteins.

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Inhibitor of growth protein 4 Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 104 amino acids
Theoretical weight: 12.4 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9UNL4 (Residues: 2-105; Coverage: 42%)
Gene names: ING4, My036
Structure domains: Helix Hairpins

Ligands and Environments

No bound ligands
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: C222
Unit cell:
a: 128.45Å b: 186.6Å c: 62.22Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.207 0.205 0.256
Expression system: Escherichia coli BL21(DE3)