X-ray diffraction
2.3Å resolution

Vinculin head (1-258) in complex with a RIAM fragment


Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Vinculin Chain: A
Molecule details ›
Chain: A
Length: 280 amino acids
Theoretical weight: 31.33 KDa
Source organism: Gallus gallus
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P12003 (Residues: 1-259; Coverage: 23%)
Gene names: VCL, VINC1
Structure domains: Alpha-catenin/vinculin-like
Amyloid beta A4 precursor protein-binding family B member 1-interacting protein Chain: B
Molecule details ›
Chain: B
Length: 32 amino acids
Theoretical weight: 3.54 KDa
Source organism: Homo sapiens
Expression system: Not provided
  • Canonical: Q7Z5R6 (Residues: 1-32; Coverage: 5%)
Gene names: APBB1IP, PREL1, RARP1, RIAM

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I24
Spacegroup: P21212
Unit cell:
a: 51.73Å b: 70.03Å c: 95.6Å
α: 90° β: 90° γ: 90°
R R work R free
0.19 0.188 0.23
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided