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Potassium bound structure of E. coli ExoIX in P21

Source organism: Escherichia coli
Biochemical function: flap endonuclease activity
Biological process: DNA replication, Okazaki fragment processing
Cellular component: not assigned

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GO terms

Sequence families

Pfam Protein families (Pfam)
PF01367
Domain description: 5'-3' exonuclease, C-terminal SAM fold
Occurring in:
  1. Flap endonuclease Xni
The deposited structure of PDB entry 3zd9 contains 1 copy of Pfam domain PF01367 (5'-3' exonuclease, C-terminal SAM fold) in Flap endonuclease Xni. Showing 1 copy in chain A.

PF02739
Domain description: 5'-3' exonuclease, N-terminal resolvase-like domain
Occurring in:
  1. Flap endonuclease Xni
The deposited structure of PDB entry 3zd9 contains 1 copy of Pfam domain PF02739 (5'-3' exonuclease, N-terminal resolvase-like domain) in Flap endonuclease Xni. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR020045
Domain description: DNA polymerase I-like, H3TH domain
Occurring in:
  1. Flap endonuclease Xni
IPR008918
Domain description: Helix-hairpin-helix motif, class 2
Occurring in:
  1. Flap endonuclease Xni
IPR036279
Domain description: 5'-3' exonuclease, C-terminal domain superfamily
Occurring in:
  1. Flap endonuclease Xni
IPR020046
Domain description: 5'-3' exonuclease, alpha-helical arch, N-terminal
Occurring in:
  1. Flap endonuclease Xni
IPR038969
Domain description: Flap endonuclease
Occurring in:
  1. Flap endonuclease Xni
IPR029060
Domain description: PIN-like domain superfamily
Occurring in:
  1. Flap endonuclease Xni
IPR002421
Domain description: 5'-3' exonuclease
Occurring in:
  1. Flap endonuclease Xni
IPR022895
Domain description: Flap endonuclease Xni
Occurring in:
  1. Flap endonuclease Xni

Structure domains

CATH CATH domains
1.10.150.20
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: DNA polymerase; domain 1
Homology: 5' to 3' exonuclease, C-terminal subdomain
Occurring in:
  1. Flap endonuclease Xni
The deposited structure of PDB entry 3zd9 contains 1 copy of CATH domain 1.10.150.20 (DNA polymerase; domain 1) in Flap endonuclease Xni. Showing 1 copy in chain A.
3.40.50.1010
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Rossmann fold
Homology: 5'-nuclease
Occurring in:
  1. Flap endonuclease Xni
The deposited structure of PDB entry 3zd9 contains 1 copy of CATH domain 3.40.50.1010 (Rossmann fold) in Flap endonuclease Xni. Showing 1 copy in chain A.

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