X-ray diffraction
2.15Å resolution

Rabbit muscle glycogen phosphorylase b in complex with N-(4- trifluoromethyl-benzoyl)-N-beta-D-glucopyranosyl urea determined at 2. 15 A resolution

Source organism: Oryctolagus cuniculus
Entry authors: Chrysina ED, Nagy V, Felfoldi N, Konya B, Telepo K, Praly JP, Docsa T, Gergely P, Alexacou KM, Hayes JM, Konstantakaki M, Kardakaris R, Leonidas DD, Zographos SE, Oikonomakos NG, Somsak L

Function and Biology Details

Reaction catalysed:
((1->4)-alpha-D-glucosyl)(n) + phosphate = ((1->4)-alpha-D-glucosyl)(n-1) + alpha-D-glucose 1-phosphate
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Glycogen phosphorylase, muscle form Chain: A
Molecule details ›
Chain: A
Length: 843 amino acids
Theoretical weight: 97.42 KDa
Source organism: Oryctolagus cuniculus
  • Canonical: P00489 (Residues: 1-843; Coverage: 100%)
Gene name: PYGM
Sequence domains: Carbohydrate phosphorylase
Structure domains: Glycogen Phosphorylase B;

Ligands and Environments

Cofactor: Ligand PLP 1 x PLP
2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX9.6
Spacegroup: P43212
Unit cell:
a: 128.65Å b: 128.65Å c: 116.903Å
α: 90° β: 90° γ: 90°
R R work R free
0.184 0.182 0.217