3wut

X-ray diffraction
2.3Å resolution

Structure basis of inactivating cell abscission

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Centrosomal protein of 55 kDa Chains: A, B, D, E, G, H, J, K
Molecule details ›
Chains: A, B, D, E, G, H, J, K
Length: 63 amino acids
Theoretical weight: 7.24 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q53EZ4 (Residues: 160-217; Coverage: 13%)
Gene names: C10orf3, CEP55, URCC6
Sequence domains: TSG101 and ALIX binding domain of CEP55
Structure domains: Geminin coiled-coil domain
Inactive serine/threonine-protein kinase TEX14 Chains: C, F, I, L
Molecule details ›
Chains: C, F, I, L
Length: 14 amino acids
Theoretical weight: 1.45 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q8IWB6 (Residues: 792-804; Coverage: 1%)
Gene names: SGK307, TEX14

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 7A (6B, 6C1)
Unit cell:
a: 53.913Å b: 102.622Å c: 132.535Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.222 0.22 0.259
Expression systems:
  • Escherichia coli
  • Not provided