PDBe 3wan

X-ray diffraction
1.77Å resolution

Crystal structure of Atg13 LIR-fused human LC3A_2-121

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Microtubule-associated proteins 1A/1B light chain 3A Chains: A, B
Molecule details ›
Chains: A, B
Length: 136 amino acids
Theoretical weight: 15.76 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9H492 (Residues: 2-121; Coverage: 99%)
  • Best match: Q9H492-2 (Residues: 18-125)
Gene name: MAP1LC3A
Sequence domains: Autophagy protein Atg8 ubiquitin like
Structure domains: Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-17A
Spacegroup: P21
Unit cell:
a: 34.73Å b: 47.88Å c: 77.08Å
α: 90° β: 94.22° γ: 90°
R-values:
R R work R free
0.176 0.174 0.227
Expression system: Escherichia coli