X-ray diffraction
2.5Å resolution

Mutant structure of Thermus thermophilus HB8 uridine-cytidine kinase


Function and Biology Details

Reaction catalysed:
ATP + cytidine = ADP + CMP
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Uridine kinase Chains: A, B
Molecule details ›
Chains: A, B
Length: 211 amino acids
Theoretical weight: 23.68 KDa
Source organism: Thermus thermophilus HB8
Expression system: Escherichia coli
  • Canonical: Q5SKR5 (Residues: 1-211; Coverage: 100%)
Gene names: TTHA0578, udk
Sequence domains: Phosphoribulokinase / Uridine kinase family
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL26B2
Spacegroup: P21212
Unit cell:
a: 68.3Å b: 124.1Å c: 60.7Å
α: 90° β: 90° γ: 90°
R R work R free
0.221 0.221 0.283
Expression system: Escherichia coli