Structure analysis

Crystal structure of Saccharomyces cerevisiae Atg8 complexed with Atg32 AIM

X-ray diffraction
3Å resolution
Assembly composition:
hetero dimer (preferred)
Entry contents: 2 distinct polypeptide molecules

Assemblies

Assembly 1 (preferred)
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Multimeric state: hetero dimer
Accessible surface area: 6700 Å2
Buried surface area: 1300 Å2
Dissociation area: 450 Å2
Dissociation energy (ΔGdiss): 4 kcal/mol
Dissociation entropy (TΔSdiss): 6 kcal/mol
Interface energy (ΔGint): -36 kcal/mol
Symmetry number: 1

Macromolecules

Chain: A
Length: 119 amino acids
Theoretical weight: 13.76 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
  • Canonical: P38182 (Residues: 1-116; Coverage: 99%)
Gene names: APG8, ATG8, AUT7, CVT5, YBL0732, YBL078C
Pfam: Autophagy protein Atg8 ubiquitin like
InterPro:
CATH: Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1

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Chain: B
Length: 6 amino acids
Theoretical weight: 732 Da
Source organism: Saccharomyces cerevisiae S288C
Expression system: Not provided
UniProt:
  • Canonical: P40458 (Residues: 85-90; Coverage: 1%)
Gene names: ATG32, ECM17, YIL146C

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