X-ray diffraction
1.8Å resolution

crystal structure of N-terminally truncated peroxiredoxin 4 from M. musculus


Function and Biology Details

Reaction catalysed:
2 R'-SH + ROOH = R'-S-S-R' + H(2)O + ROH
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Peroxiredoxin-4 Chains: A, B
Molecule details ›
Chains: A, B
Length: 209 amino acids
Theoretical weight: 23.61 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
  • Canonical: O08807 (Residues: 87-274; Coverage: 80%)
Gene name: Prdx4
Sequence domains: C-terminal domain of 1-Cys peroxiredoxin
Structure domains: Glutaredoxin

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL44XU
Spacegroup: I4
Unit cell:
a: 104.321Å b: 104.321Å c: 84.228Å
α: 90° β: 90° γ: 90°
R R work R free
0.155 0.153 0.193
Expression system: Escherichia coli