PDBe 3vkm

X-ray diffraction
2.98Å resolution

Protease-resistant mutant form of Human Galectin-8 in complex with sialyllactose and lactose

Released:

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Galectin-8 Chains: A, B
Molecule details ›
Chains: A, B
Length: 291 amino acids
Theoretical weight: 33.11 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O00214 (Residues: 1-155, 184-317; Coverage: 91%)
Gene name: LGALS8
Sequence domains: Galactoside-binding lectin
Structure domains: Jelly Rolls

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE AR-NW12A
Spacegroup: P212121
Unit cell:
a: 74.133Å b: 80.713Å c: 129.296Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.2 0.2 0.261
Expression system: Escherichia coli