PDBe 3v4o

X-ray diffraction
2.1Å resolution

Human MALT1 (caspase domain) in complex with an irreversible peptidic inhibitor


Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 Chain: A
Molecule details ›
Chain: A
Length: 245 amino acids
Theoretical weight: 27.71 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
  • Canonical: Q9UDY8 (Residues: 329-569; Coverage: 29%)
Gene names: MALT1, MLT
Sequence domains: Caspase domain
Structure domains: Rossmann fold
MALT1 Inhibitor Chain: B
Molecule details ›
Chain: B
Length: 6 amino acids
Theoretical weight: 697 Da
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P6122
Unit cell:
a: 77.5Å b: 77.5Å c: 180.493Å
α: 90° β: 90° γ: 120°
R R work R free
0.179 0.176 0.228
Expression systems:
  • Spodoptera frugiperda
  • Not provided