X-ray diffraction
2Å resolution

Crystal structure of renal tumor suppressor protein, folliculin


Function and Biology Details

Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Entry contents:
1 distinct polypeptide molecule
Folliculin Chains: A, B
Molecule details ›
Chains: A, B
Length: 226 amino acids
Theoretical weight: 25.47 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q8NFG4 (Residues: 341-566; Coverage: 39%)
Gene names: BHD, FLCN
Sequence domains: Folliculin C-terminal domain
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I02
Spacegroup: C2221
Unit cell:
a: 86.05Å b: 99.951Å c: 107.584Å
α: 90° β: 90° γ: 90°
R R work R free
0.207 0.204 0.268
Expression system: Escherichia coli