3uzc

X-ray diffraction
3.34Å resolution

Thermostabilised Adenosine A2A receptor in complex with 4-(3-amino-5-phenyl-1,2,4-triazin-6-yl)-2-chlorophenol

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Adenosine receptor A2a Chain: A
Molecule details ›
Chain: A
Length: 329 amino acids
Theoretical weight: 36.48 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P29274 (Residues: 1-317; Coverage: 77%)
Gene names: ADORA2, ADORA2A
Sequence domains: 7 transmembrane receptor (rhodopsin family)
Structure domains: Rhodopsin 7-helix transmembrane proteins

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I24
Spacegroup: I222
Unit cell:
a: 110.7Å b: 112.064Å c: 126.9Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.282 0.282 0.29
Expression system: Spodoptera frugiperda