› 3ux8

X-ray diffraction
2.1Å resolution

Crystal structure of UvrA

Released:
DOI: 10.2210/pdb3ux8/pdb
PDB entry 3ux8 coloured by chain, front view.
PDB entry 3ux8 coloured by chain, side view.
PDB entry 3ux8 coloured by chain, top view.
Source organism: Geobacillus sp. Y412MC52
Primary publication:
Structure and mechanism of the UvrA-UvrB DNA damage sensor.
Pakotiprapha D, Samuels M, Shen K, Hu JH, Jeruzalmi D
Nat Struct Mol Biol 19 291-8 (2012)
PMID: 22307053

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-101165 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
UvrABC system protein A Chain: A
Molecule details ›
Chain: A
Length: 670 amino acids
Theoretical weight: 73.72 KDa
Source organism: Geobacillus sp. Y412MC52
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A0E0TG05 (Residues: 4-955; Coverage: 68%)
Gene names: GYMC52_3203, uvrA

Ligands and Environments

2 bound ligands:
Ligand ZN 1 x ZN
Ligand ADP 1 x ADP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: C2
Unit cell:
a: 128.653Å b: 51.33Å c: 112.395Å
α: 90° β: 97.27° γ: 90°
R-values:
R R work R free
0.212 0.21 0.245
Expression system: Escherichia coli

Quick links

Citations

13 review citations

Prokaryotic nucleotide excision repair.
Kisker et al. (2013)
12 more

3 mentions without citation

A Peek Inside the Machines of Bacterial Nucleotide Excision Repair.
Kraithong et al. (2021)
2 more