X-ray diffraction
2.9Å resolution

The GLIC pentameric Ligand-Gated Ion Channel Loop2-21' mutant reduced in solution

Source organism: Gloeobacter violaceus
Entry authors: Sauguet L, Nury H, Corringer PJ, Delarue M

Function and Biology Details

Structure analysis Details

Assembly composition:
homo pentamer (preferred)
Entry contents:
1 distinct polypeptide molecule
Proton-gated ion channel Chains: A, B, C, D, E, F, G, H, I, J
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J
Length: 321 amino acids
Theoretical weight: 36.52 KDa
Source organism: Gloeobacter violaceus
Expression system: Escherichia coli
  • Canonical: Q7NDN8 (Residues: 44-359; Coverage: 100%)
Gene names: glr4197, glvI
Sequence domains: Neurotransmitter-gated ion-channel ligand binding domain
Structure domains:

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: C2
Unit cell:
a: 182.13Å b: 133.49Å c: 319.69Å
α: 90° β: 102.64° γ: 90°
R R work R free
0.218 0.218 0.221
Expression system: Escherichia coli