X-ray diffraction
2.25Å resolution

Crystal structure of Aspergillus fumigatus UDP galactopyranose mutase complexed with UDP in reduced state

Source organism: Aspergillus fumigatus
Entry authors: Dhatwalia R, Singh H, Tanner JJ

Function and Biology Details

Reaction catalysed:
UDP-alpha-D-galactopyranose = UDP-alpha-D-galactofuranose
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
UDP-galactopyranose mutase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 513 amino acids
Theoretical weight: 57.13 KDa
Source organism: Aspergillus fumigatus
Expression system: Escherichia coli
  • Canonical: Q4W1X2 (Residues: 1-510; Coverage: 100%)
Gene names: glf, glfA
Sequence domains: NAD(P)-binding Rossmann-like domain
Structure domains: FAD/NAD(P)-binding domain

Ligands and Environments

Cofactor: Ligand FDA 4 x FDA
2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.2
Spacegroup: P6522
Unit cell:
a: 218.176Å b: 218.176Å c: 320.822Å
α: 90° β: 90° γ: 120°
R R work R free
0.193 0.192 0.218
Expression system: Escherichia coli