X-ray diffraction
2.75Å resolution

Crystal structure of R182K-UDP-galactopuranose mutase from Aspergillus fumigatus in complex with UDPgalp


Function and Biology Details

Reaction catalysed:
UDP-alpha-D-galactopyranose = UDP-alpha-D-galactofuranose
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
UDP-galactopyranose mutase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 517 amino acids
Theoretical weight: 57.87 KDa
Source organism: Aspergillus fumigatus
Expression system: Escherichia coli BL21(DE3)
  • Canonical: Q4W1X2 (Residues: 2-510; Coverage: 100%)
Gene names: glf, glfA
Sequence domains: NAD(P)-binding Rossmann-like domain
Structure domains: FAD/NAD(P)-binding domain

Ligands and Environments

Cofactor: Ligand FDA 3 x FDA

Cofactor: Ligand FAD 1 x FAD
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08B1-1
Spacegroup: P21
Unit cell:
a: 70.66Å b: 123.66Å c: 156.37Å
α: 90° β: 103.26° γ: 90°
R R work R free
0.186 0.183 0.241
Expression system: Escherichia coli BL21(DE3)