X-ray diffraction
2.64Å resolution

CRYSTAL STRUCTURE OF UDP-galactopyranose mutase from Aspergillus fumigatus


Function and Biology Details

Reaction catalysed:
UDP-alpha-D-galactopyranose = UDP-alpha-D-galactofuranose
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
UDP-galactopyranose mutase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 509 amino acids
Theoretical weight: 57.48 KDa
Source organism: Aspergillus fumigatus
Expression system: Escherichia coli BL21(DE3)
  • Canonical: Q4W1X2 (Residues: 2-510; Coverage: 100%)
Gene names: glf, glfA
Sequence domains: NAD(P)-binding Rossmann-like domain
Structure domains: FAD/NAD(P)-binding domain

Ligands and Environments

Cofactor: Ligand FAD 4 x FAD
No bound ligands
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: P1
Unit cell:
a: 69.83Å b: 73.56Å c: 116.01Å
α: 102.02° β: 101.07° γ: 91.11°
R R work R free
0.209 0.206 0.267
Expression system: Escherichia coli BL21(DE3)