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Crystal structure of human PDI bb'a' domains

X-ray diffraction
2.29Å resolution
PDB entry 3uem coloured by chain, front view.
PDB entry 3uem coloured by chain, side view.
PDB entry 3uem coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Protein disulfide-isomerase
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Multimeric state: monomeric
Accessible surface area: 18960.94 Å2
Buried surface area: 378.25 Å2
Dissociation area: 189.12 Å2
Dissociation energy (ΔGdiss): -0.42 kcal/mol
Dissociation entropy (TΔSdiss): 2.02 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-139447

Macromolecules

Protein disulfide-isomerase
Chain: A
Length: 361 amino acids
Theoretical weight: 40.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P07237 (Residues: 137-479; Coverage: 70%)
Gene names: ERBA2L, P4HB, PDI, PDIA1, PO4DB
Pfam:
InterPro:
CATH: Glutaredoxin
Protein disulfide-isomerase in PDB entry 3uem, assembly 1, front view.
Protein disulfide-isomerase in PDB entry 3uem, assembly 1, side view.
Protein disulfide-isomerase in PDB entry 3uem, assembly 1, top view.
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