› 3ue6

X-ray diffraction
2.75Å resolution

The dark structure of the blue-light photoreceptor Aureochrome1 LOV

Released:
DOI: 10.2210/pdb3ue6/pdb
PDB 3ue6 coloured by chain and viewed from the front.
PDB 3ue6 coloured by chain and viewed from the side.
PDB 3ue6 coloured by chain and viewed from the top.
Source organism: Vaucheria frigida
Primary publication:
Crystal structures of Aureochrome1 LOV suggest new design strategies for optogenetics.
Mitra D, Yang X, Moffat K
Structure 20 698-706 (2012)
PMID: 22483116

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
homo dimer (preferred)
homo hexamer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Aureochrome1 Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 166 amino acids
Theoretical weight: 18.47 KDa
Source organism: Vaucheria frigida
Expression system: Escherichia coli
UniProt:
  • Canonical: A8QW55 (Residues: 176-337; Coverage: 47%)
Gene name: AUREO1
Sequence domains: PAS domain
Structure domains: PAS domain

Ligands and Environments

2 bound ligands:
Ligand FMN 6 x FMN
Ligand PO4 2 x PO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 14-BM-C
Spacegroup: P43
Unit cell:
a: 73.987Å b: 73.987Å c: 177.468Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.196 0.192 0.256
Expression system: Escherichia coli

Quick links

Citations

8 review citations

Aureochromes - Blue Light Receptors.
Matiiv et al. (2018)
7 more

2 mentions without citation

Blue light-induced LOV domain dimerization enhances the affinity of Aureochrome 1a for its target DNA sequence.
Heintz et al. (2016)
1 more