X-ray diffraction
2.8Å resolution

The c-di-GMP-I riboswitch bound to pGpG


Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
1 distinct polypeptide molecule
2 distinct RNA molecules
Macromolecules (3 distinct):
U1 small nuclear ribonucleoprotein A Chain: P
Molecule details ›
Chain: P
Length: 98 amino acids
Theoretical weight: 11.34 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
  • Canonical: P09012 (Residues: 1-98; Coverage: 35%)
Gene name: SNRPA
Sequence domains: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Structure domains: Alpha-Beta Plaits
RNA (92-MER) Chain: R
Molecule details ›
Chain: R
Length: 92 nucleotides
Theoretical weight: 29.94 KDa
Source organism: Vibrio cholerae
Expression system: Not provided
Sequence domains: Cyclic di-GMP-I riboswitch
diguanosine monophosphate Chain: A
Molecule details ›
Chain: A
Length: 2 nucleotides
Theoretical weight: 645 Da
Source organism: Vibrio cholerae
Expression system: Not provided

Ligands and Environments

1 bound ligand:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X25
Spacegroup: P21
Unit cell:
a: 49.088Å b: 45.35Å c: 77.243Å
α: 90° β: 96.24° γ: 90°
R R work R free
0.217 0.215 0.262
Expression systems:
  • Escherichia coli BL21
  • Not provided