PDBe 3ub2

X-ray diffraction
2.4Å resolution

TIR domain of Mal/TIRAP

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Toll/interleukin-1 receptor domain-containing adapter protein Chain: A
Molecule details ›
Chain: A
Length: 146 amino acids
Theoretical weight: 15.97 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P58753 (Residues: 78-221; Coverage: 65%)
Gene names: MAL, TIRAP
Sequence domains: TIR domain
Structure domains: Toll/interleukin-1 receptor homology (TIR) domain

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P43212
Unit cell:
a: 87.508Å b: 87.508Å c: 81.684Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.249 0.248 0.262
Expression system: Escherichia coli