› › Function and Biology

Crystal structure of adenosine phosphorylase from Bacillus cereus complexed with adenosine

Source organism: Bacillus cereus
Biochemical function: pentosyltransferase activity
Biological process: purine nucleoside metabolic process
Cellular component: cytosol

Quick links

EC 2.4.2.1: Purine-nucleoside phosphorylase

Reaction catalysed:
Purine deoxynucleoside + phosphate = purine + 2'-deoxy-alpha-D-ribose 1-phosphate
Systematic name:
Purine-nucleoside:phosphate ribosyltransferase
Alternative Name(s):
  • Inosine phosphorylase
  • Inosine-guanosine phosphorylase
  • Nucleotide phosphatase
  • PNPase
  • PUNPI
  • PUNPII
  • Purine deoxynucleoside phosphorylase
  • Purine deoxyribonucleoside phosphorylase
  • Purine nucleoside phosphorylase
  • Purine ribonucleoside phosphorylase

GO terms

Sequence family

Pfam Protein family (Pfam)
PF01048
Domain description: Phosphorylase superfamily
Occurring in:
  1. Purine nucleoside phosphorylase DeoD-type
The deposited structure of PDB entry 3uaw contains 1 copy of Pfam domain PF01048 (Phosphorylase superfamily) in Purine nucleoside phosphorylase DeoD-type. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR004402
Domain description: Purine nucleoside phosphorylase DeoD-type
Occurring in:
  1. Purine nucleoside phosphorylase DeoD-type
IPR035994
Domain description: Nucleoside phosphorylase superfamily
Occurring in:
  1. Purine nucleoside phosphorylase DeoD-type
IPR018016
Domain description: Nucleoside phosphorylase, conserved site
Occurring in:
  1. Purine nucleoside phosphorylase DeoD-type
IPR000845
Domain description: Nucleoside phosphorylase domain
Occurring in:
  1. Purine nucleoside phosphorylase DeoD-type

Structure domain

CATH CATH domain
3.40.50.1580
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Rossmann fold
Homology: Nucleoside phosphorylase domain
Occurring in:
  1. Purine nucleoside phosphorylase DeoD-type
The deposited structure of PDB entry 3uaw contains 1 copy of CATH domain 3.40.50.1580 (Rossmann fold) in Purine nucleoside phosphorylase DeoD-type. Showing 1 copy in chain A.

Quick links