PDBe 3u86

X-ray diffraction
2.84Å resolution

Crystal structure of human menin in complex with JunD

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Menin Chain: A
Molecule details ›
Chain: A
Length: 550 amino acids
Theoretical weight: 61.06 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O00255 (Residues: 2-615; Coverage: 89%)
  • Best match: O00255-2 (Residues: 2-610)
Gene names: MEN1, SCG2
Sequence domains: Menin
Transcription factor jun-D Chain: B
Molecule details ›
Chain: B
Length: 15 amino acids
Theoretical weight: 1.53 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P17535 (Residues: 27-39; Coverage: 4%)
Gene name: JUND

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-D
Spacegroup: P41212
Unit cell:
a: 140.647Å b: 140.647Å c: 93.106Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.22 0.217 0.245
Expression system: Escherichia coli BL21(DE3)