Structure analysis

The pleckstrin homology (PH) domain of USP37

X-ray diffraction
2.08Å resolution
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1
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Multimeric state: monomeric
Accessible surface area: 6600 Å2
Buried surface area: 3200 Å2
Dissociation area: 100 Å2
Dissociation energy (ΔGdiss): 1 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Interface energy (ΔGint): -118 kcal/mol
Symmetry number: 1
Assembly 2 (preferred)
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Multimeric state: monomeric

Binding statistics and energies are not available for this assembly

Macromolecules

Chains: A, B
Length: 141 amino acids
Theoretical weight: 15.84 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q86T82 (Residues: 4-125; Coverage: 13%)
Gene names: KIAA1594, USP37
InterPro:
CATH: Ubiquitin carboxyl-terminal hydrolase 26/29/37, pleckstrin homology-like domain

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