› 3tx2

X-ray diffraction
1.5Å resolution

Function and Biology Details

Reaction catalysed: 
6-phospho-D-glucono-1,5-lactone + H(2)O = 6-phospho-D-gluconate
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-109335 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
6-phosphogluconolactonase Chain: A
Molecule details ›
Chain: A
Length: 251 amino acids
Theoretical weight: 26.54 KDa
Source organism: Mycobacteroides abscessus ATCC 19977
Expression system: Escherichia coli
UniProt:
  • Canonical: B1MC71 (Residues: 1-247; Coverage: 100%)
Gene names: MAB_2763, pgl
Sequence domains: Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
Structure domains: Rossmann fold

Ligands and Environments

3 bound ligands:
Ligand NA 2 x NA
Ligand GOL 1 x GOL
Ligand BEZ 1 x BEZ
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: P21212
Unit cell:
a: 136.35Å b: 41.18Å c: 44.97Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.193 0.192 0.211
Expression system: Escherichia coli

Quick links

Citations

6 review citations

Pleiotropic Functions of Tumor Suppressor WWOX in Normal and Cancer Cells.
Abu-Remaileh et al. (2015)
5 more